Article
Soluble factors regulated by epithelial-mesenchymal transition mediate tumour angiogenesis and myeloid cell recruitment.
The Journal of pathology - 1 Aug 2015
Suarez-Carmona Meggy, Bourcy Morgane, Lesage Julien, Leroi Natacha, Syne Laïdya, Blacher Silvia, Hubert Pascale, Erpicum Charlotte, Foidart Jean-Michel, Delvenne Philippe, Birembaut Philippe, Noël Agnès, Polette Myriam, Gilles Christine
Abstract excerpt
Epithelial-mesenchymal transition (EMT) programmes provide cancer cells with invasive and survival capacities that might favour metastatic dissemination. Whilst signalling cascades triggering EMT have been extensively studied, the impact of EMT on the crosstalk between tumour cells and the tumour microenvironment remains elusive. We aimed to identify EMT-regulated soluble factors that facilitate the recruitment...
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