Article
Mitochondrial haplogroups and control region polymorphisms in Kaposi's sarcoma patients.
Journal of medical virology - 1 Sept 2015
Jalilvand Somayeh, Shoja Zabihollah, Marashi Sayed Mahdi, Shahmahmoodi Shohreh, Safaie-Naraghi Zahra, Nourijelyani Keramat, Nesheli Asgar Baghernejad, Mokhtari-Azad Talat
Abstract excerpt
Inflammation and reactive oxygen species (ROS) production have recently considered as key mechanisms in the pathogenesis of Kaposi's sarcoma (KS). Since mitochondria are the major source of ROS production, this organelle may play a main role in KS development. However, there are no studies on mtDNA variations and haplogroups in this area. The focus of this study was to investigate the mtDNA variants and...
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