Article
Antibody escape kinetics of equine infectious anemia virus infection of horses.
Journal of virology - 1 Jul 2015
Schwartz Elissa J, Nanda Seema, Mealey Robert H
Abstract excerpt
Lentivirus escape from neutralizing antibodies (NAbs) is not well understood. In this work, we quantified antibody escape of a lentivirus, using antibody escape data from horses infected with equine infectious anemia virus. We calculated antibody blocking rates of wild-type virus, fitness costs of mutant virus, and growth rates of both viruses. These quantitative kinetic estimates of antibody escape are important...
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