Article
Immune selection of equine infectious anemia virus env variants during the long-term inapparent stage of disease.
Virology - 20 Jun 2007
Sponseller Brett A, Sparks Wendy O, Wannemuehler Yvonne, Li Yuxing, Antons Amanda K, Oaks J Lindsay, Carpenter Susan
Abstract excerpt
The principal neutralizing domain (PND) of equine infectious anemia virus (EIAV) is located in the V3 region of SU. Genetic variation in the PND is considered to play an important role in immune escape and EIAV persistence; however, few studies have characterized genetic variation in SU during the inapparent stage of disease. To better understand the mechanisms of virus persistence, we undertook a longitudinal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
