Article
Decreased infectivity of a neutralization-resistant equine infectious anemia virus variant can be overcome by efficient cell-to-cell spread.
Journal of virology - 1 Oct 2011
Wu Wuwei, Blythe Derek C, Loyd Hyelee, Mealey Robert H, Tallmadge Rebecca L, Dorman Karin S, Carpenter Susan
Abstract excerpt
Two variants of equine infectious anemia virus (EIAV) that differed in sensitivity to broadly neutralizing antibody were tested in direct competition assays. No differences were observed in the growth curves and relative fitness scores of EIAVs of principal neutralizing domain variants of groups 1 (EIAV(PND-1)) and 5 (EIAV(PND-5)), respectively; however, the neutralization-resistant EIAV(PND-5) variant was less...
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