Article
[Association of UGT1A1 (*28, *60 and * 93) polymorphism with the adverse reactions of irinotecan chemotherapy in extensive stage small cell lung cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jan 2015
Ma Lixia, Chen Yan, Yang Changliang, Jiang Hui, Zhu Jing, Cheng Ying
Abstract excerpt
OBJECTIVE: To explore the correlation between UGT1A1 (*28, *60 and * 93) polymorphism and the adverse reactions in small cell lung cancer patients after irinotecan chemotherapy. METHODS: Clinical data of 58 small cell lung cancer patients in extensive stage treated in our hospital were retrospectively analyzed. Polymerase chain reaction was used to amplify the UTG, and direct sequencing was performed to determine...
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