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Article

Uridine diphosphate glucuronide transferase 1A1FNx0128 gene polymorphism and the toxicity of irinotecan in recurrent and refractory small cell lung cancer.

Journal of cancer research and therapeutics - 1 Nov 2014

Yun Fan, Lulu Miao, Zhiyu Huang, Lei Gong, Haifeng Yu, Tao Lei, Haiyan Yang, Conghua Xie

Abstract excerpt

OBJECTIVE: The aim was to investigate the association between uridine diphosphate glucuronide transferase 1A1 (UGT1A1) gene promoter region polymorphism and irinotecan-related adverse effects and efficacy on recurrent and refractory small cell lung cancer (SCLC). MATERIALS AND METHODS: A total of 31 patients with recurrent and refractory SCLC were enrolled in this study from June 2012 to August 2013 and received...

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Identifiers

PMID: 25450281
DOI: 10.4103/0973-1482.145871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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