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Article

Low cytochrome oxidase 4I1 links mitochondrial dysfunction to obesity and type 2 diabetes in humans and mice.

International journal of obesity (2005) - 1 Aug 2015

Van der Schueren B, Vangoitsenhoven R, Geeraert B, De Keyzer D, Hulsmans M, Lannoo M, Huber H J, Mathieu C, Holvoet P

Abstract excerpt

OBJECTIVES: Cytochrome oxidase (COX) dysfunction is associated with mitochondrial oxidative stress. We determined the association between COX expression, obesity and type 2 diabetes. SUBJECTS/METHODS: COX4I1 and COX10 genes were measured in monocytes of 24 lean controls, 31 glucose-tolerant and 67 diabetic obese patients, and 17 morbidly obese patients before and after bariatric surgery. We investigated the...

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Alkyl and Aryl Transferases
Bariatric Surgery
Diabetes Mellitus, Experimental
Electron Transport
Electron Transport Complex IV

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Obesity, Morbid

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PMID: 25869607
DOI: 10.1038/ijo.2015.58

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COX10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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