Article
Meningioma in Down Syndrome.
World neurosurgery - 1 Sept 2015
Yamamoto Takahiro, Shinojima Naoki, Todaka Tatemi, Nishikawa Shigeyuki, Yano Shigetoshi, Kuratsu Jun-ichi
Abstract excerpt
BACKGROUND: Down syndrome comprises multiple malformations and is due to trisomy of chromosome 21. There is epidemiologic evidence that individuals with Down syndrome are at decreased risk for solid tumors including brain tumors. It has been suggested that some genes expressed on the extra copy of chromosome 21 act as tumor suppressor genes and contribute to protection against tumorigenesis. CASE DESCRIPTION: We...
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