Article
Genetic contribution to variation in DNA methylation at maternal smoking-sensitive loci in exposed neonates.
Epigenetics - 1 Sept 2016
Gonseth Semira, de Smith Adam J, Roy Ritu, Zhou Mi, Lee Seung-Tae, Shao Xiaorong, Ohja Juhi, Wrensch Margaret R, Walsh Kyle M, Metayer Catherine, Wiemels Joseph L
Abstract excerpt
Epigenome-wide DNA methylation association studies have identified highly replicable genomic loci sensitive to maternal smoking during gestation. The role of inter-individual genetic variation in influencing DNA methylation, leading to the possibility of confounding or bias of such associations, has not been assessed. We investigated whether the DNA methylation levels at the top 10 CpG sites previously associated...
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