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Article

Role of ASXL1 and TP53 mutations in the molecular classification and prognosis of acute myeloid leukemias with myelodysplasia-related changes.

Oncotarget - 10 Apr 2015

Devillier Raynier, Mansat-De Mas Véronique, Gelsi-Boyer Veronique, Demur Cecile, Murati Anne, Corre Jill, Prebet Thomas, Bertoli Sarah, Brecqueville Mandy, Arnoulet Christine, Recher Christian, Vey Norbert, Mozziconacci Marie-Joelle, Delabesse Eric, Birnbaum Daniel

Abstract excerpt

Acute myeloid leukemias (AML) with myelodysplasia-related changes (AML-MRC) are defined by the presence of multilineage dysplasia (MLD), and/or myelodysplastic syndrome (MDS)-related cytogenetics, and/or previous MDS. The goal of this study was to identify distinct biological and prognostic subgr...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25860933
DOI: 10.18632/oncotarget.3460
PMCID: PMC4480760

Genes

ASXL1
FLT3
NPM1
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25860933-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Role of ASXL1 and TP53 mutations in the molecular classification and prognosis of acute myeloid leukemias with myelodysplasia-related changes.PMID 25860933Read ↗

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