Article
The paradox of high availability and low recognition of soluble HLA-G by LILRB1 receptor in rheumatoid arthritis patients.
PloS one - 1 Jan 2015
Veit Tiago Degani, Chies José Artur Bogo, Switala Magdalena, Wagner Bettina, Horn Peter A, Busatto Mauricio, Brenol Claiton Viegas, Tavares Brenol João Carlos, Machado Xavier Ricardo, Rebmann Vera
Abstract excerpt
HLA-G is a regulatory molecule involved in immunologic tolerance. Growing evidence indicates that HLA-G plays a role in the regulation of inflammatory processes and autoimmune diseases. This study aimed at a systematic evaluation of soluble HLA-G (sHLA-G) in plasma of rheumatoid arthritis (RA) patients with long-lasting chronic inflammation. RA patients (n=68) and healthy controls (n=26) had their plasmatic...
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