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Article

New insights into the pathology of pulmonary hypertension: implication of the miR-210/ISCU1/2/Fe-S axis.

EMBO molecular medicine - 1 Jun 2015

Tang Haiyang, Ayon Ramon J, Yuan Jason X-J

Abstract excerpt

Elevated pulmonary arterial pressure in patients with pulmonary hypertension (PH) is mainly caused by increased pulmonary vascular resistance (PVR), due primarily to sustained pulmonary vasoconstriction and excessive pulmonary vascular remodeling. According to the current classification, PH has been classified into five categories based on etiology (Simonneau et al, 2013). Among them, group 1 or pulmonary...

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Topics

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Share to PVR gene
Share to Genetic Predisposition to Disease
Share to Hypertension, Pulmonary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypoxia

Share to Iron Deficiencies

Share to Iron-Sulfur Proteins

Share to MicroRNAs

Share to Sulfur

Source

Open in PubMed Open full text

Identifiers

PMID: 25851536
DOI: 10.15252/emmm.201505160
PMCID: PMC4459811

Genes

PAH
PVR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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