Article
Identifying potential ferroptosis-related biomarkers and therapeutic targets for Idiopathic Pulmonary Hypertension in the context of predictive, preventive, and personalized medicine by integrative bioinformatics approaches
2024-02-01
Abstract excerpt
<h4>Background: </h4> Idiopathic pulmonary arterial hypertension (IPAH), a rare and devastating pulmonary vascular disorder, is characterized by cellular proliferation and vascular remodeling. Although previous studies have underscored that ferroptosis, an iron-dependent cell death process, plays an important regulatory role in pulmonary artery hypertension, its role remains understudied. Therefore, the identifica...
Topics
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- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Connective Tissue Growth Factor Research
- Ferroptosis and cancer prognosis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- MicroRNA in disease regulation
- Pulmonary Hypertension Research and Treatments
- RNA modifications and cancer
Identifiers and source
- Literature Corpus work
- e0bb068a-5137-54e0-b5ae-b53a966786cc
- DOI
- 10.21203/rs.3.rs-3903471/v1
