Article
Ras/MEK/MAPK-mediated regulation of heparin sulphate proteoglycans promotes retinal fate in the Drosophila eye-antennal disc.
Developmental biology - 1 Jun 2015
Fernandes Vilaiwan M, Pradhan-Sundd Tirthadipa, Blaquiere Jessica A, Verheyen Esther M
Abstract excerpt
Generating cellular heterogeneity is crucial to the development of complex organs. Organ-fate selector genes and signalling pathways generate cellular diversity by subdividing and patterning naïve tissues to assign them regional identities. The Drosophila eye-antennal imaginal disc is a well-characterised system in which to study regional specification; it is first divided into antennal and eye fates and...
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