IFI35, mir-99a and HCV genotype to predict sustained virological response to pegylated-interferon plus ribavirin in chronic hepatitis C.

doi:10.1371/journal.pone.0121395

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Article

IFI35, mir-99a and HCV genotype to predict sustained virological response to pegylated-interferon plus ribavirin in chronic hepatitis C.

PloS one - 1 Jan 2015

Estrabaud Emilie, Appourchaux Kevin, Bièche Ivan, Carrat Fabrice, Lapalus Martine, Lada Olivier, Martinot-Peignoux Michelle, Boyer Nathalie, Marcellin Patrick, Vidaud Michel, Asselah Tarik

Abstract excerpt

Although, the treatment of chronic hepatitis C (CHC) greatly improved with the use of direct antiviral agents, pegylated-interferon (PEG-IFN) plus ribavirin remains an option for many patients, worldwide. The intra-hepatic level of expression of interferon stimulated genes (ISGs) and the rs12979860 CC genotype located within IFNL3 have been associated with sustained virological response (SVR), in patients with...

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Identifiers

PMID: 25844942
DOI: 10.1371/journal.pone.0121395
PMCID: PMC4386819

Genes

IFI35
IFNL3

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Source receipt: pubmed, retrieved 7 Sept 2026.

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