Article
Epigenetic regulation of metabolism in children born small for gestational age.
Current opinion in clinical nutrition and metabolic care - 1 Jul 2006
Holness Mark J, Sugden Mary C
Abstract excerpt
PURPOSE OF REVIEW: Epigenetic alterations are responsible for modulation of tissue-specific gene expression and genomic imprinting. Mechanisms include posttranslational modifications of core histones and DNA methylation. The review focuses on emerging data highlighting the potential for epigenetic modulation of gene expression in mediating early-life programming of increased risk of adult-onset disease. To...
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