Article
Enhancer blocking and transvection at the Drosophila apterous locus.
Genetics - 1 Jan 2008
Gohl Daryl, Müller Martin, Pirrotta Vincenzo, Affolter Markus, Schedl Paul
Abstract excerpt
Intra- and interchromosomal interactions have been implicated in a number of genetic phenomena in diverse organisms, suggesting that the higher-order structural organization of chromosomes in the nucleus can have a profound impact on gene regulation. In Drosophila, homologous chromosomes remain paired in somatic tissues, allowing for trans interactions between genes and regulatory elements on the two homologs....
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