Article
Risk factors for endometrial cancer among women with a BRCA1 or BRCA2 mutation: a case control study.
Familial cancer - 1 Sept 2015
Segev Yakir, Rosen Barry, Lubinski Jan, Gronwald Jacek, Lynch Henry T, Moller Pal, Kim-Sing Charmaine, Ghadirian Parviz, Karlan Beth, Eng Charis, Gilchrist Dawna, Neuhausen Susan L, Eisen Andrea, Friedman Eitan, Euhus David, Ping Sun, Narod Steven A
Abstract excerpt
BRCA mutation carriers may use tamoxifen for breast cancer prevention or treatment. Hormone replacement therapy is often prescribed after surgical menopause and oral contraceptives are recommended for ovarian cancer prevention. The objective of this study was to assess the impact of these medications and other risk factors on endometrial cancer risk in BRCA carriers. Women with a BRCA1 or BRCA2 mutation were...
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