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Article

Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study.

The Lancet. Oncology - 1 Jan 2007

McLaughlin John R, Risch Harvey A, Lubinski Jan, Moller Pal, Ghadirian Parviz, Lynch Henry, Karlan Beth, Fishman David, Rosen Barry, Neuhausen Susan L, Offit Kenneth, Kauff Noah, Domchek Susan, Tung Nadine, Friedman Eitan, Foulkes William, Sun Ping, Narod Steven A

Abstract excerpt

BACKGROUND: Several of the known risk factors for ovarian cancer are thought to act through their effects on ovulation and the menstrual cycle, such as parity, breastfeeding, and use of oral contraceptives. We aimed to assess the effect of these three risk factors, and of tubal ligation, on the risk of ovarian cancer in women who carry a mutation in the BRCA1 or BRCA2 genes. METHODS: We did a matched case-control...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17196508
DOI: 10.1016/S1470-2045(06)70983-4

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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