Article
Antithrombin heparin binding site deficiency: A challenging diagnosis of a not so benign thrombophilia.
Thrombosis research - 1 Jun 2015
Orlando Christelle, Heylen Olivier, Lissens Willy, Jochmans Kristin
Abstract excerpt
BACKGROUND: Hereditary antithrombin (AT) deficiency is a rare autosomal dominant disorder characterised by decreased AT activity in plasma and predisposition to recurrent venous thromboembolism (VTE). Thrombotic risk is thought to vary according to the subtype of deficiency, with Heparin Binding Site (HBS) deficiencies being the less thrombogenic. OBJECTIVES AND METHODS: The study population consisted of 82...
Topics
- Adolescent
- Adult
- Antithrombin III
- Antithrombin III Deficiency
- Antithrombins
- Arteries
- Binding Sites
- Child
- Child, Preschool
- Factor V
- Female
- Heparin