Article
Antithrombin Cambridge II (A384S): an underestimated genetic risk factor for venous thrombosis.
Blood - 15 May 2007
Corral Javier, Hernandez-Espinosa David, Soria Jose Manual, Gonzalez-Conejero Rocio, Ordonez Adriana, Gonzalez-Porras Jose Ramon, Perez-Ceballos Elena, Lecumberri Ramon, Sanchez Ignacio, Roldan Vanessa, Mateo Jose, Minano Antonia, Gonzalez Marcos, Alberca Ignacio, Fontcuberta Jordi, Vicente Vicente
Abstract excerpt
The antithrombin A384S mutation has a relatively high frequency in the British population but has not been identified in other populations. This variant has been associated with cases of thrombotic disease, but its clinical relevance in venous thrombosis remained unclear. We have conducted a secondary analysis of the prevalence of the mutation in a large case-control study, including 1018 consecutive Spanish...
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