Article
Ex vivo and in vitro production of pro-inflammatory cytokines in Blau syndrome.
Reumatismo - 31 Mar 2015
Galozzi P, Negm O, Greco E, Alkhattabi N, Gava A, Sfriso P, Fairclough L, Todd I, Tighe P, Punzi L
Abstract excerpt
The objective was to study both ex vivo and in vitro secretion of pro-inflammatory cytokines in patients affected by Blau syndrome (BS) and carrying p.E383K mutation in the CARD15/NOD2 gene associated with the disease. For ex vivo studies, peripheral blood mononuclear cells (PBMCs), serum from three patients and healthy controls have been collected. PBMCs have been cultured in the presence or absence of...
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