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Article

Preserved otolith organ function in caspase-3-deficient mice with impaired horizontal semicircular canal function.

Experimental brain research - 1 Jun 2015

Armstrong Patrick A, Wood Scott J, Shimizu Naoki, Kuster Kael, Perachio Adrian, Makishima Tomoko

Abstract excerpt

Genetically engineered mice are valuable models for elucidation of auditory and vestibular pathology. Our goal was to establish a comprehensive vestibular function testing system in mice using: (1) horizontal angular vestibulo-ocular reflex (hVOR) to evaluate semicircular canal function and (2) otolith-ocular reflex (OOR) to evaluate otolith organ function and to validate the system by characterizing mice with...

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Identifiers

PMID: 25827332
DOI: 10.1007/s00221-015-4254-4
PMCID: PMC4439373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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