Article
Association study of PDE4B with panic disorder in the Japanese population.
Progress in neuro-psychopharmacology & biological psychiatry - 30 Mar 2011
Otowa Takeshi, Kawamura Yoshiya, Sugaya Nagisa, Yoshida Eiji, Shimada Takafumi, Liu Xiaoxi, Tochigi Mamoru, Umekage Tadashi, Miyagawa Taku, Nishida Nao, Kaiya Hisanobu, Okazaki Yuji, Tokunaga Katsushi, Sasaki Tsukasa
Abstract excerpt
BACKGROUND: Panic disorder (PD) is a severe and chronic psychiatric disorder with genetic components underlying in its etiology. The Phosphodiesterase 4B (PDE4B) gene has been reported to be associated with several psychiatric disorders. Several studies indicated that PDE4B may be involved in the regulation of anxiety and depression. Therefore, we investigate the association of PDE4B with PD in the Japanese...
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