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Article

Use of Monte Carlo simulation to evaluate the development of vancomycin resistance in meticillin-resistant Staphylococcus aureus.

International journal of antimicrobial agents - 1 Jun 2015

Mei Qing, Ye Ying, Zhu Yu-lin, Cheng Jun, Yang Hai-fei, Liu Yan-yan, Li Hong-ru, Li Jia-bin

Abstract excerpt

Monte Carlo simulations were performed for various vancomycin dosage regimens to evaluate the potential for development of vancomycin resistance in meticillin-resistant Staphylococcus aureus (MRSA). When the target of free AUC(24)/MIC≥200 was considered (where AUC(24) is the area under the drug concentration-time curve in a 24-h interval and MIC is the minimum inhibitory concentration), a standard dose regimen...

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Identifiers

PMID: 25813394
DOI: 10.1016/j.ijantimicag.2015.01.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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