Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vancomycin exposure in patients with methicillin-resistant Staphylococcus aureus bloodstream infections: how much is enough?

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Sept 2014

Lodise Thomas P, Drusano George L, Zasowski Evan, Dihmess Amanda, Lazariu Victoria, Cosler Leon, McNutt Louise-Anne

Abstract excerpt

BACKGROUND: Contemporary vancomycin dosing schemes are designed to achieve an area under the curve (AUC) to minimum inhibitory concentration (MIC) ratio of ≥400. However, scant clinical data exist to support this target and available data relied on pharmacokinetic formulas based on daily vancomycin dose and estimated renal function (demographic pharmacokinetic model) to estimate AUCs. METHODS: A cohort study of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Area Under Curve
Share to Bacteremia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bayes Theorem

Share to Methicillin-Resistant Staphylococcus aureus

Share to Microbial Sensitivity Tests

Share to Staphylococcal Infections

Share to Treatment Failure

Share to Vancomycin

Source

Identifiers

PMID: 24867791
DOI: 10.1093/cid/ciu398

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vancomycin exposure in patients with methicillin-resistant Staphylococcus aureus bloodstream infections: how much is enough?PMID 24867791Read ↗

Determining vancomycin Etest MICs in patients with MRSA bloodstream infection does not support switching antimicrobials.Semantic proximity Read ↗

Serum Concentration of Continuously administered Vancomycin influences Efficacy and Safety in Critically Ill Adults: A Systematic ReviewSemantic proximity Read ↗

Impact of Vancomycin trough levels monitoring on uncomplicated methilcillin-resistant Staphylococcus aureus bacteremia in chronic kidney disease on hemodialysis, retrospective cohortSemantic proximity Read ↗

Machine learning models for vancomycin dose estimation in hospitalized adults and adolescentsSemantic proximity Read ↗

Can clinical and molecular epidemiologic parameters guide empiric treatment with vancomycin for methicillin-resistant Staphylococcus aureus infections?Semantic proximity Read ↗

Treatment of bacteraemia: meticillin-resistant Staphylococcus aureus (MRSA) to vancomycin-resistant S. aureus (VRSA).Semantic proximity Read ↗

Vancomycin MIC plus heteroresistance and outcome of methicillin-resistant Staphylococcus aureus bacteremia: trends over 11 years.Semantic proximity Read ↗

Use of Monte Carlo simulation to evaluate the development of vancomycin resistance in meticillin-resistant Staphylococcus aureus.Semantic proximity Read ↗

Impact of reduced vancomycin MIC on clinical outcomes of methicillin-resistant Staphylococcus aureus bacteremia.Semantic proximity Read ↗

Vancomycin Population Pharmacokinetic Models in Non- Critically Ill Adults Patients: a scoping reviewSemantic proximity Read ↗

Nosocomial methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in Taiwan: mortality analyses and the impact of vancomycin, MIC = 2 mg/L, by the broth microdilution method.Semantic proximity Read ↗

Individualized Meropenem Dosing in CRRT Patients: Development and Validation of a Machine Learning-Based Decision Support ToolSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.