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Article

Cell adhesion down-regulates the expression of vacuolar protein sorting 4B (VPS4B) and contributes to drug resistance in multiple myeloma cells.

International journal of hematology - 1 Jul 2015

Tang Jie, Ji Lili, Wang Yuchan, Huang Yuejiao, Yin Haibing, He Yunhua, Liu Jing, Miao Xiaobing, Wu Yaxun, Xu Xiaohong, He Song, Cheng Chun

Abstract excerpt

The expression and biologic function of the gene encoding vacuolar protein sorting 4B (VPS4B) in human multiple myeloma (MM) were investigated in this study. We determined that VPS4B expression is decreased in adherent MM cells and that knockdown of VPS4B expression induces cell adhesion-mediated...

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Identifiers

PMID: 25804841
DOI: 10.1007/s12185-015-1783-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25804841-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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