Article
Analysis of a single Helicobacter pylori strain over a 10-year period in a primate model.
International journal of medical microbiology : IJMM - 1 May 2015
Liu Hui, Fero Jutta B, Mendez Melissa, Carpenter Beth M, Servetas Stephanie L, Rahman Arifur, Goldman Matthew D, Boren Thomas, Salama Nina R, Merrell D Scott, Dubois Andre
Abstract excerpt
Helicobacter pylori from different individuals exhibits substantial genetic diversity. However, the kinetics of bacterial diversification after infection with a single strain is poorly understood. We investigated evolution of H. pylori following long-term infection in the primate stomach; Rhesus macaques were infected with H. pylori strain USU101 and then followed for 10 years. H. pylori was regularly cultured...
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