Article
Inducible Expression of a Resistance-Nodulation-Division-Type Efflux Pump in Staphylococcus aureus Provides Resistance to Linoleic and Arachidonic Acids.
Journal of bacteriology - 1 Jun 2015
Alnaseri Heba, Arsic Benjamin, Schneider James E T, Kaiser Julienne C, Scinocca Zachariah C, Heinrichs David E, McGavin Martin J
Abstract excerpt
UNLABELLED: Although Staphylococcus aureus is exposed to antimicrobial fatty acids on the skin, in nasal secretions, and in abscesses, a specific mechanism of inducible resistance to this important facet of innate immunity has not been identified. Here, we have sequenced the genome of S. aureus USA300 variants selected for their ability to grow at an elevated concentration of linoleic acid. The fatty...
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