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Recent Insights into the Control of Human Papillomavirus (HPV) Genome Stability, Loss, and Degradation

27 Jan 2015

Abstract excerpt

Most human papillomavirus (HPV) antiviral strategies have focused upon inhibiting viral DNA replication, but it is increasingly apparent that viral DNA levels can be chemically controlled by approaches that promote its instability. HPVs and other DNA viruses have a tenuous relationship with their hosts. They must replicate and hide from the DNA damage response (DDR) and innate immune systems, which serve to...

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PMID: 25798290
DOI: 10.3390/jcm4020204

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