Article
Phosphorelay of non-orthodox two component systems functions through a bi-molecular mechanism in vivo: the case of ArcB.
Molecular bioSystems - 1 May 2015
Jovanovic Goran, Sheng Xia, Ale Angelique, Feliu Elisenda, Harrington Heather A, Kirk Paul, Wiuf Carsten, Buck Martin, Stumpf Michael P H
Abstract excerpt
Two-component systems play a central part in bacterial signal transduction. Phosphorelay mechanisms have been linked to more robust and ultra-sensitive signalling dynamics. The molecular machinery that facilitates such a signalling is, however, only understood in outline. In particular the functional relevance of the dimerization of a non-orthodox or hybrid histidine kinase along which the phosphorelay takes...
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