Article
Characterizing the interactions between a naturally primed immunoglobulin A and its conserved Bacteroides thetaiotaomicron species-specific epitope in gnotobiotic mice.
The Journal of biological chemistry - 15 May 2015
Peterson Daniel A, Planer Joseph D, Guruge Janaki L, Xue Lai, Downey-Virgin Whitt, Goodman Andrew L, Seedorf Henning, Gordon Jeffrey I
Abstract excerpt
The adaptive immune response to the human gut microbiota consists of a complex repertoire of antibodies interacting with a broad range of taxa. Fusing intestinal lamina propria lymphocytes from mice monocolonized with Bacteroides thetaiotaomicron to a myeloma fusion partner allowed us to recover...
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