Article
Patient-specific mathematical neuro-oncology: using a simple proliferation and invasion tumor model to inform clinical practice.
Bulletin of mathematical biology - 1 May 2015
Jackson Pamela R, Juliano Joseph, Hawkins-Daarud Andrea, Rockne Russell C, Swanson Kristin R
Abstract excerpt
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor associated with a poor median survival of 15-18 months, yet there is wide heterogeneity across and within patients. This heterogeneity has been the source of significant clinical challenges facing patients with GBM and has hampered the drive toward more precision or personalized medicine approaches to treating these challenging tumors....
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