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Article

Kinetic evaluation of photosensitivity in bi-stable variants of chimeric channelrhodopsins.

PloS one - 1 Jan 2015

Hososhima Shoko, Sakai Seiichiro, Ishizuka Toru, Yawo Hiromu

Abstract excerpt

Channelrhodopsin-1 and 2 (ChR1 and ChR2) form cation channels that are gated by light through an unknown mechanism. We tested the DC-gate hypothesis that C167 and D195 are involved in the stabilization of the cation-permeable state of ChRWR/C1C2 which consists of TM1-5 of ChR1 and TM6-7 of ChR2 and ChRFR which consists of TM1-2 of ChR1 and TM3-7 of ChR2. The cation permeable state of each ChRWR and ChRFR was...

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Identifiers

PMID: 25789474
DOI: 10.1371/journal.pone.0119558
PMCID: PMC4366085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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