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Article

Association of Toll-like receptor 2 Arg753Gln and Toll-like receptor 1 Ile602Ser single-nucleotide polymorphisms with leptospirosis in an Argentine population.

Acta tropica - 1 Jun 2015

Cédola Maia, Chiani Yosena, Pretre Gabriela, Alberdi Lucrecia, Vanasco Bibiana, Gómez Ricardo M

Abstract excerpt

Toll-like receptor 2 (TLR2), a member of the Toll-like receptor family, plays an important role in the recognition of and subsequent immune response activation against leptospirosis in humans. The genetic polymorphism in TLR2 of an arginine to glutamine substitution at residue 753 (Arg753Gln) has been associated with a negative influence on TLR2 function, which may, in turn, determine the innate host response to...

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Source

Identifiers

PMID: 25784560
DOI: 10.1016/j.actatropica.2015.03.007

Genes

TLR2
TLR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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