Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in KISS1 are not responsible for idiopathic hypogonadotropic hypogonadism in Chinese patients.

Journal of assisted reproduction and genetics - 1 Mar 2015

Zhang Yiming, Zhang Haobo, Qin Yingying, Zhang Yingchun, Chen Xinxia, Li Weiping, Chen Zi-Jiang

Abstract excerpt

PURPOSE: To investigate whether mutations in the KISS1 gene are present in 170 Chinese patients with idiopathic hypogonadotropic hypogonadism (IHH). METHODS: Mutational screening of the KISS1 gene was performed in 170 Chinese patients with IHH (133 male cases and 37 female cases) and 187 matched controls (94 males and 93 females). RESULTS: Two known single-nucleotide polymorphisms (SNP), c. 58G > A in exon 1 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Genotype

Share to Hypogonadism

Share to Kisspeptins

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 25783047
DOI: 10.1007/s10815-014-0424-8
PMCID: PMC4363243

Genes

KISS1
IHH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in KISS1 are not responsible for idiopathic hypogonadotropic hypogonadism in Chinese patients.PMID 25783047Read ↗

Homozygous mutation of KISS1 receptor (KISS1R) gene identified in a Chinese patient with congenital hypogonadotropic hypogonadism (CHH): case report and literature review.Semantic proximity Read ↗

Novel KISS1 Gene Mutation Leading to Male Hypogonadotropic Hypogonadism.Semantic proximity Read ↗

A novel homozygous splice acceptor site mutation of KISS1R in two siblings with normosmic isolated hypogonadotropic hypogonadism.Semantic proximity Read ↗

Identification of KISS1R gene mutations in disorders of non-obstructive azoospermia in the northeast population of China.Semantic proximity Read ↗

KISS1 Gene Variations and Susceptibility to Idiopathic Recurrent Pregnancy Loss.Semantic proximity Read ↗

GnRH-deficient phenotypes in humans and mice with heterozygous variants in KISS1/Kiss1.Semantic proximity Read ↗

rs4889 and rs5782018 polymorphisms of KISS1 gene as genetic predisposing factor for PCOS in Indonesian womenSemantic proximity Read ↗

Molecular genetic analysis of normosmic hypogonadotropic hypogonadism in a Turkish population: identification and detailed functional characterization of a novel mutation in the gonadotropin-releasing hormone receptor gene.Semantic proximity Read ↗

Association study of the polymorphisms in the KISS1 gene with central precocious puberty in Chinese girls.Semantic proximity Read ↗

Prevalence of KISS1 Receptor mutations in a series of 603 patients with normosmic congenital hypogonadotrophic hypogonadism and characterization of novel mutations: a single-centre study.Semantic proximity Read ↗

KISS1 gene analysis in Korean girls with central precocious puberty: a polymorphism, p.P110T, suggested to exert a protective effectSemantic proximity Read ↗

Novel FGFR1 and KISS1R Mutations in Chinese Kallmann Syndrome Males with Cleft Lip/Palate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.