Article
Investigating the Effect of rs3783605 Single-nucleotide Polymorphism on the Activity of VCAM-1 Promoter in Human Umbilical Vein Endohelial Cells.
Iranian journal of allergy, asthma, and immunology - 1 Apr 2015
Dadgar Pakdel Fatemeh, Keramatipour Mohammad, Noorbakhsh Farshid, Talebi Saeed, Vodjgani Mohammad
Abstract excerpt
The interaction between immune cells and endothelial lining of blood vessels is vital in many processes such as inflammatory and immune responses as well as cancer cell metastasis. The expression level of VCAM-1 is regulated by many factors including the promoter activity that is possibly affected by the single nucleotide polymorphisms (SNPs) present in the promoter. There are previous reports suggesting an...
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