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Article

Dumbbell-PCR: a method to quantify specific small RNA variants with a single nucleotide resolution at terminal sequences.

Nucleic acids research - 13 Jul 2015

Honda Shozo, Kirino Yohei

Abstract excerpt

Recent advances in next-generation sequencing technologies have revealed that cellular functional RNAs are not always expressed as single entities with fixed terminal sequences but as multiple isoforms bearing complex heterogeneity in both length and terminal sequences, such as isomiRs, the isoforms of microRNAs. Unraveling the biogenesis and biological significance of heterogenetic RNA expression requires...

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Identifiers

PMID: 25779041
DOI: 10.1093/nar/gkv218
PMCID: PMC4499115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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