Article
Polymorphisms of GSTA1 contribute to elevated cancer risk: evidence from 15 studies.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Deng Qiwen, He Bangshun, Pan Yuqin, Sun Huiling, Liu Xian, Chen Jie, Ying Houqun, Lin Kang, Peng Hongxin, Wang Shukui
Abstract excerpt
PURPOSE: Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens, and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. However, the studies about the effect of GSTA1 polymorphisms on cancer risk are limited and the conclusions are contradictory. This meta-analysis aimed to evaluate the association between GSTA1...
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