Article
Association of facilitated glucose transporter 2 gene variants with the myelomeningocele phenotype.
Birth defects research. Part A, Clinical and molecular teratology - 1 Jun 2015
Ruggiero Jaclyn E, Northrup Hope, Au Kit Sing
Abstract excerpt
BACKGROUND: Neural tube defects (NTDs) remain the second most common cause of congenital malformations. Myelomeningocele (MM), the most common NTD compatible with survival, results from genetic and environmental factors. Epidemiologic studies and murine models support the hypotheses that obesity, diabetes and hyperglycemia confer increased risk of NTDs. Presence of wild-type facilitated glucose transporter,...
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