Article
PPARD rs2016520 polymorphism and circulating lipid levels connect with brain diseases in Han Chinese and suggest sex-dependent effects.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Mar 2015
Huang Yi, Nie Sheng, Zhou Shengjun, Li Keqin, Sun Jie, Zhao Jikuang, Fei Bing, Wang Zhepei, Ye Huadan, Hong Qingxiao, Gao Xiang, Duan Shiwei
Abstract excerpt
The PPARD polymorphisms were shown to be associated with circulating lipoprotein metabolism in various diseases. We aimed to check the contribution of PPARD rs2016520 and lipid concentration to the risk of intracerebral hemorrhages (ICH) and brain tumors (BT) in Han Chinese. A total of 864 participants were included in the case-control study. The melting temperature shift (Tm-shift) method was used for rs2016520...
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