Article
A functional variant in promoter region of platelet-derived growth factor-D is probably associated with intracerebral hemorrhage.
Journal of neuroinflammation - 30 Jan 2012
Bai Yongyi, Chen Jingzhou, Sun Kai, Wang Yibo, Hui Rutai
Abstract excerpt
BACKGROUND: Platelet-derived growth factor D (PDGF-D) plays an important role in angiogenesis, vessel remodeling, inflammation and repair in response to injury. We hypothesized that genetic variation in PDGFD gene might alter the susceptibility to stroke. FINDINGS: We determined the genotypes of a single nucleotide polymorphism (SNP) (-858A/C, rs3809021) in 1484 patients with stroke (654 cerebral thrombosis, 419...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
