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Article

MiR-2 family regulates insect metamorphosis by controlling the juvenile hormone signaling pathway.

Proceedings of the National Academy of Sciences of the United States of America - 24 Mar 2015

Lozano Jesus, Montañez Raúl, Belles Xavier

Abstract excerpt

In 2009 we reported that depletion of Dicer-1, the enzyme that catalyzes the final step of miRNA biosynthesis, prevents metamorphosis in Blattella germanica. However, the precise regulatory roles of miRNAs in the process have remained elusive. In the present work, we have observed that Dicer-1 depletion results in an increase of mRNA levels of Krüppel homolog 1 (Kr-h1), a juvenile hormone-dependent transcription...

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Source

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Identifiers

PMID: 25775510
DOI: 10.1073/pnas.1418522112
PMCID: PMC4378413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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