Article
Enhanced functions of peripheral γδ T cells in chronic hepatitis B infection during interferon α treatment in vivo and in vitro.
PloS one - 1 Jan 2015
Chen Min, Hu Peng, Ling Ning, Peng Hui, Lei Yu, Hu Huaidong, Zhang Dazhi, Ren Hong
Abstract excerpt
BACKGROUND: γδ T cells play an important role in infectious, autoimmune, or neoplastic diseases. Here, a study was conducted to investigate the dynamic changes in phenotype and function of peripheral γδ T cells in patients with chronic hepatitis B (CHB) during pegylated-interferon (pegIFN)-α treatment, and to explore their roles in IFN-α therapy. METHODS: Total 15 CHB patients with pegIFN-α therapy and 6 healthy...
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