Article
Genetic variations in the SOCS3 gene in patients with Graves' ophthalmopathy.
Journal of clinical pathology - 1 Jun 2015
Yan Ruijia, Yang Junjie, Jiang Ping, Jin Ling, Ma Jing, Huang Rong, Ma Nan, Jiang Fagang
Abstract excerpt
AIMS: To explore the role of the suppressor of cytokine signalling 3 (SOCS3) gene in Graves' ophthalmopathy (GO) patients. METHODS: A case-control study was conducted in a Chinese Han population by recruiting 114 Graves' disease (GD) patients with GO and 156 GD patients without GO. We determined SOCS3 mRNA and protein levels in Epstein-Barr virus-transformed lymphoblastoid cell lines (EBV-LCLs) from peripheral...
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