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Article

HPV Clearance and the Neglected Role of Stochasticity

13 Mar 2015

Abstract excerpt

Clearance of anogenital and oropharyngeal HPV infections is attributed primarily to a successful adaptive immune response. To date, little attention has been paid to the potential role of stochastic cell dynamics in the time it takes to clear an HPV infection. In this study, we combine mechanistic mathematical models at the cellular level with epidemiological data at the population level to disentangle the...

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PMID: 25769112
DOI: 10.1371/journal.pcbi.1004113

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