Article
Bacteria and bacterial rRNA genes associated with the development of colitis in IL-10(-/-) mice.
Inflammatory bowel diseases - 1 Aug 2008
Ye Jingxiao, Lee Jimmy W, Presley Laura L, Bent Elizabeth, Wei Bo, Braun Jonathan, Schiller Neal L, Straus Daniel S, Borneman James
Abstract excerpt
BACKGROUND: Microorganisms appear to play important yet ill-defined roles in the etiology of inflammatory bowel disease (IBD). This study utilized a novel population-based approach to identify bacteria and bacterial rRNA genes associated with the development of colitis in IL-10(-/-) mice. METHODS: Mice were housed in 2 environments: a community mouse facility where the mice were fed nonsterile chow (Room 3) and a...
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