Article
The commensal microbiota and enteropathogens in the pathogenesis of inflammatory bowel diseases.
Gastroenterology - 1 May 2011
Chassaing Benoit, Darfeuille-Michaud Arlette
Abstract excerpt
Intestinal inflammation arises from abnormal host-microbe interactions. The perturbations of homeostatic coexistence involve host genetic factors, barrier function, innate and adaptive immunity, as well as qualitative and quantitative changes in the composition of the microbiota. Dysbiosis toward selected micro-organisms and decreased complexity of commensal bacteria have been observed in patients with Crohn's...
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