Article
Role of nitric oxide in the genotoxic response to chronic microcystin-LR exposure in human-hamster hybrid cells.
Journal of environmental sciences (China) - 1 Mar 2015
Wang Xiaofei, Huang Pei, Liu Yun, Du Hua, Wang Xinan, Wang Meimei, Wang Yichen, Hei Tom K, Wu Lijun, Xu An
Abstract excerpt
Microcystin-LR (MC-LR) is the most abundant and toxic microcystin congener and has been classified as a potential human carcinogen (Group 2B) by the International Agency for Research on Cancer. However, the mechanisms underlying the genotoxic effects of MC-LR during chronic exposure are still poorly understood. In the present study, human-hamster hybrid (AL) cells were exposed to MC-LR for varying lengths of time...
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